Protein Characterization by Mass Spectrometry

Sponsors:

Symposium:

This symposium has two (2) sessions of invited speakers listed below. Presenters whose topics relate to this symposium are invited to contribute papers to associated session(s) of oral and poster presentations.

Invited Speakers:

Organizer:

Ken Tomer (The National Institute of Environmental Health Science)

When and Where:

Both invited and contributed sessions will be held in the Sheraton Imperial Hotel and Convention Center. The invited session is scheduled on Thursday, November 11, 2004 and Friday, November 12, 2004. The contributed papers and posters related to this symposium will be coordinated with the invited session. Posters should be sized to fit a 4' x 8' poster board. (Sheraton Floor Plan)

Abstracts:

John Fenn "ELECTROSPRAY WINGS FOR MOLECULAR ELEPHANTS"

Small effusive leaks into vacuum systems, as in Knudsen cells and classical molecular beam machines, made many contributions to science in the twentieth century. They have continued to serve both science and technology in the early years of the twenty first century. Beginning in the 1950s, big convective leaks have turned out to be even more powerful and versatile tools. The supersonic free jets produced by these big leaks have greatly extended molecular beam methods, become a corner-stone of cluster science and technology, and rewritten the book on molecular spectroscopy. Those jets are now adding new dimensions to the techniques of mass spectrometry by making possible the production of intact ions from the large, complex and fragile species that play such vital roles in living systems. The path from the first crude experiments of Dunoyer into the groves of atomic and molecular physics followed along the trail blazed by Otto Stern and his disciples. That trail was then extended into the fertile fields of chemistry, by the likes of Herschbach, Lee, Polanyi, Smalley, Zare and Zewail, five of whom received Nobel Prizes for their contributions. More recently that trail entered the lush gardens of biology where mass spectrometry is providing bumper crops of information and understanding. This travelogue will describe some of the landmarks along what has been a fascinating journey.

Disclaimer:

This is a working document and changes will be made until the program is finalized.

Updated: September 7, 2004
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bill_switzer@ncsu.edu